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Anti-Somatostatin Receptor Type 1 antibody produced in rabbit
| 产品编号： | 3397120 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 50 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Somatostatin Receptor Type 1 antibody produced in rabbit
Anti-SSTR1
基本信息
| MDL number | MFCD02097418 |
| NACRES | NA.41 |
| General description【一般描述】 | Somatostatin Receptor Type 1 (SSTR1) is present in blood vessels, neuroendocrine cells, and the retina. SSTR1 gene is mapped to human chromosome 14q21.1. |
| Immunogen【免疫原】 | synthetic peptide corresponding to the C-terminal of human somatostatin receptor type 1, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene. |
| Biochem/physiol Actions【生化/生理作用】 | Somatostatin Receptor Type 1 (SSTR1) protein extracellular loop regions are crucial for ligand binding. SSTR1 gene down-regulated in reported in preeclampsia but it is overexpressed in breast cancer. It is reported to block the mitogen-activated protein kinase (MAPK) pathway. However, in pancreatic cell lines, elevated expression of SSTR1 gene favors cell cycle arrest. SSTR1 also plays a tumor suppressor role in gastric cancer invasion. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 8 μg/mL using human pancreas, Islets of Langerhans |
| UniProt accession no.【UniProt登记号】 | P30872 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SSTR1(6751) mouse ... Sstr1(20605) rat ... Sstr1(25033) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
