Anti-SRP14 antibody produced in rabbit

NA.41

Signal recognition particle 14 kDa (homologous Alu RNA binding protein) (SRP14) is a component of eukaryotic signal recognition particle (SRP) ribonucleoprotein that directs the traffic of proteins within cells and allows them to be secreted. The heterodimeric subunit, SRP9/14, of the signal recognition particle (SRP) bind to scALu and scB1 RNAs.

Anti-SRP14 polyclonal antibody reacts with human, canine, chicken, bovine, mouse, zebrafish, and rat signal recognition particle 14 kDa proteins.

Synthetic peptide directed towards the N terminal region of human SRP14

Anti-SRP14 polyclonal antibody is used to tag signal recognition particle 14 kDa for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of signal recognition particle 14 kDa in ribonucleoprotein structure and function.

SRP14 belongs to the SRP14 family. The signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

Synthetic peptide located within the following region: KPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLL

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

15 kDa

horse, dog, bovine, human, rabbit, rat, guinea pig, sheep

0.5 mg - 1 mg/mL

immunohistochemistry: suitable
western blot: suitable

NP_003125

P37108

wet ice

−20℃

human ... SRP14(6727)

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12 - Non Combustible Liquids

WGK 3