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Anti-ST3GAL6 antibody produced in rabbit
产品编号: | 3398124 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-ST3GAL6 antibody produced in rabbit
Anti-siat10
Anti-3-sialyltransferase 6
Anti-ST3Gal VI
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | rat, mouse, human |
technique(s) | immunocytochemistry: suitable indirect ELISA: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_006091 |
UniProt accession no.【UniProt登记号】 | Q9Y274 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ST3GAL6(10402) |
基本信息
Immunogen【免疫原】 | ST3gal6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human ST3gal6. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500045. |
Physical form【外形】 | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
产品说明
Target description【目标描述】 | Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |