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Anti-Substance P antibody produced in rabbit
产品别名
Anti-Substance P antibody produced in rabbit
Anti-SP
基本信息
MDL number | MFCD00162870 |
NACRES | NA.41 |
General description【一般描述】 | Substance P (SP) is widely distributed throughout the central nervous system (CNS) and peripheral nervous system, including the brain, spinal cord, primary sensory neurons and intrinsic nerve fibers associated with the gastrointestinal (GI) tract. Substance P (SP) is a 11 amino acid peptide. It is a member of tachykinins family, that includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1 It is located on human chromosome 7q21.3. |
Immunogen【免疫原】 | synthetic Substance P (SP), conugated to KLH. |
Application【应用】 | Anti-Substance P antibody has been used in immunostaining and immunohistochemistry. |
Biochem/physiol Actions【生化/生理作用】 | Substance P (SP) improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, trigger glandular secretion and controls autonomic reflexes. It plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer. Substance P (SP) is a neurotransmitter or neuromodulator. SP mediates the process of neurogenic inflammation. |
Analysis Note【分析说明】 | The antiserum is evaluated for activity and specificity by dot blot immunoassay and RIA. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | whole antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
contains【包含】 | 15 mM sodium azide |
species reactivity | cat, pig, human, bovine, monkey, rat |
technique(s) | dot blot: 1:20,000 radioimmunoassay: 1:5,000 |
UniProt accession no.【UniProt登记号】 | P20366 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TAC1(6863) rat ... Tac1(24806) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |