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Anti-SUZ12 (AB2) antibody produced in rabbit
产品别名
Anti-SUZ12 (AB2) antibody produced in rabbit
Anti-CHET9
Anti-KIAA0160
Anti-Suppressor of zeste 12 homolog (Drosophila)
Anti-JJAZ1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | SUZ12 is a zinc-finger protein that is needed for the silencing and histone methyltransferase functions of the EED-EZH2 complex. SUZ12 is also known to be associated with all-trans retinoic acid response elements (RAREs). Rabbit Anti-SUZ12 antibody recognizes human, mouse, and bovine SUZ12. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human SUZ12 |
| Application【应用】 | Rabbit Anti-SUZ12 is suitable for western blot applications at a concentration of 1 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7;17)(p15;q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Sequence【序列】 | Synthetic peptide located within the following region: ESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 83 kDa |
| species reactivity | human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_056170 |
| UniProt accession no.【UniProt登记号】 | Q15022 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SUZ12(23512) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
