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Anti-TEX14 antibody produced in rabbit
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产品别名
Anti-TEX14 antibody produced in rabbit
Anti-Testis expressed 14
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human TEX14 |
Application【应用】 | Anti-TEX14 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
Biochem/physiol Actions【生化/生理作用】 | TEX14 (Testis expressed 14) gene encodes a protein that contains three ankyrin repeats, a protein kinase domain and a leucine zipper dimerization motif. The mRNA of the encoded protein is predominantly expressed in the testis. TEX14 is essential for intercellular bridge formation during meiosis as well as in mitosis it facilitates the kinetochore-microtubule attachment. TEX14 interacts with CEP55 and inhibits the GPPX3Y motifs of ALIX and TSG101 from interacting and confining to the midbody. Hence, TEX14 blocks the cell abscission and transform midbodies into intercellular bridges. |
Sequence【序列】 | Synthetic peptide located within the following region: ASSDTLVAVEKSYSTSSPIEEDFEGIQGAFAQPQVSGEEKFQMRKILGKN |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 160 kDa |
species reactivity | human |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_938207 |
UniProt accession no.【UniProt登记号】 | Q8IWB6 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TEX14(56155) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |