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Anti-TIE2, C-Terminal antibody produced in rabbit
产品别名
Anti-TIE2, C-Terminal antibody produced in rabbit
hTIE2
p140 TEK
Tunica interna endothelial cell kinase
Tyrosine-protein kinase receptor TEK
Tyrosine-protein kinase receptor TIE-2
基本信息
| MDL number | MFCD02264171 |
| NACRES | NA.41 |
| General description【一般描述】 | The TIE2 (TEK receptor tyrosine kinase) gene is mapped to human chromosome 9p21.2. It is predominantly expressed in the Schlemm′s canal endothelial of the eye. Anti-TIE2 Antibody detects endogenous levels of total TIE2 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human TIE2. Immunogen Range: 1068-1117 |
| Biochem/physiol Actions【生化/生理作用】 | Tie-2 (TEK receptor tyrosine kinase) protein induces angiogenesis (both developmental and tumor) and supports endothelial cell survival, upon binding of angiopoietin-1 (an endothelial growth factor) to the receptor. Tie-2 is necessary for Schlemm′s canal formation. The gene regulates vascular homeostasis by involving in auto or transphosphorylation. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 125 kDa |
| species reactivity | mouse, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunohistochemistry: 1:50-1:100 |
| NCBI accession no.【NCBI登记号】 | Q02763 |
| UniProt accession no.【UniProt登记号】 | Q02763 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TEK(7010) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
