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Anti-TLR6 antibody produced in rabbit
产品别名
Anti-TLR6 antibody produced in rabbit
Anti-toll-like receptor 6
基本信息
| MDL number | MFCD03456043 |
| NACRES | NA.41 |
| General description【一般描述】 | TLR6 is a member of the toll-like receptor family and activates NF-κB and c-Jun N-terminal kinase (JNK). TLR6 polymorphisms have been linked to the risk of invasive aspergillosis. Rabbit Anti-TLR6 antibody recognizes human TLR6. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human TLR6 |
| Application【应用】 | Rabbit Anti-TLR6 antibody can be used for western blot (1.0μg/ml) and immunohistochemical (4-8μg/ml, using paraffin embedded tissues) assays. |
| Biochem/physiol Actions【生化/生理作用】 | TLR6 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. |
| Sequence【序列】 | Synthetic peptide located within the following region: KCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHIT |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 53 kDa |
| species reactivity | human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_006059 |
| UniProt accession no.【UniProt登记号】 | Q2NKL3 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TLR6(10333) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
