Anti-ULBP1 antibody produced in rabbit

HPA007547    Human Protein Atlas characterization data

ULBP1 (Unique Long 16 binding protein 1) gene encodes a ligand for KLRK1/NKG2D (natural killer cell lec-tin-like receptor gene 2D) receptor. It consists of α1 and α2 domains, which are connected to the cell surface through glycosylphosphatidylinositol.This receptor is expressed on natural killer (NK) cells, NKT cells, γδ⁺ T cells and CD₈⁺ T cells.

NKG2D ligand 1 precursor recombinant protein epitope signature tag (PrEST)

Anti-ULBP1 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

ULBP1 (Unique Long 16 binding protein 1) functions as a stimulatory immune receptor and is expressed on natural killer (NK) cells, NKT cells, γδ+ T cells and CD⁸⁺ T cells. The expression of this ligand is stimulated upon infection and other inducers of cellular stress. This ligand binds to the receptor and initiates an immune response by activating multiple signaling pathways in primary NK cells. It serves as a prognostic marker in cervical cancer.

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

• IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
• Protein array of 364 human recombinant protein fragments.

Corresponding Antigen APREST71802.

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

Prestige Antibodies^® Powered by Atlas Antibodies

buffered aqueous glycerol solution

human

antibody small pack of 25 μL

orthogonal RNAseq
Learn more about Antibody Enhanced Validation

immunohistochemistry: 1:50- 1:200

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Q9BZM6

wet ice

−20℃

human ... ULBP1(80329)

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10 - Combustible liquids

WGK 1

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)