Anti-VIP36/ LMAN2 antibody produced in rabbit

NA.41

Anti-VIP36/LMAN2 is produced in rabbit using as immunogen a synthetic peptide of human LMAN2 conjugated to KLH. VIP36 (vesicular-integral protein of 36 kDa) is a member of the leguminous-type (L-type) lectin family, which also includes ERGIC-53, ERGL and VIPL. L-type lectins are type I transmembrane proteins composed of a large luminal domain comprising a carbohydrate recognition domain (CRD) and a short cytosolic domain that mediates sorting within the early secretory pathway. VIP36 localizes mainly to the Golgi apparatus and cycles between the Golgi and the ER.

Anti-VIP36/ LMAN2 antibody produced in rabbit has been used in immunoblotting.

Vesicular-integral protein of 36 kDa (VIP36) binds high mannose type glycoproteins in a Ca²⁺-dependent manner and may facilitate their sorting, trafficking and quality control.

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen ~36 kDa

human, mouse, rat

~1.0 mg/mL

western blot: 2.5-5.0 μg/mL using whole extracts of human HeLa or ACHN cells, rat Rat2 or mouse 3T3 cells.

Q12907

dry ice

−20℃

human ... LMAN2(10960)
mouse ... Lman2(66890)
rat ... Lman2(290994)

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