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Anti-WAVE1 antibody produced in rabbit
产品别名
Anti-WAVE1 antibody produced in rabbit
Verprolin homology domain-containing protein 1
WAS1
SCAR1
KIAA0269
WASF1
基本信息
| MDL number | MFCD04118689 |
| NACRES | NA.41 |
| General description【一般描述】 | Wiskott–aldrich syndrome protein family member 1 (WAVE1) is encoded by the gene mapped to human chromosome 6q21-22. It is primarily expressed in brain and is characterized with a tripartite VCA (verprolin homology, cofilin homology and acidic) domain. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human WAVE1. Immunogen Range: 91-140 |
| Application【应用】 | Anti-WAVE1 antibody produced in rabbit has been used in immunoblotting. |
| Biochem/physiol Actions【生化/生理作用】 | Members of WASP-family verprolin-homologous protein (WAVE) family plays a vital role in actin polymerisation and cytoskeletal organisation, which are essential for various cellular processes, including cell shape changes, cytokinesis, cell motility and membrane traffic. WAVE1 regulates chemoresistance during autophagy. The encoded protein plays an essential role in oligodendrocyte morphogenesis and myelination. In addition, it is also implicated in regulation of spine morphogenesis. Overexpression of the gene leads to the development of prostate cancer. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 61 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q92558 |
| UniProt accession no.【UniProt登记号】 | Q92558 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... WASF1(8936) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
