Anti-WDYHV1 (center) antibody produced in rabbit

NA.41

Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine

WDYHV1 (NP_060494, 111-146)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human WDYHV1.

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

rabbit

100

unconjugated

saturated ammonium sulfate (SAS) precipitated

primary antibodies

polyclonal

buffered aqueous solution

mouse, human

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NP_060494

Q96HA8

dry ice

−20℃

human ... WDYHV1(55093)

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12 - Non Combustible Liquids

nwg