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AUDA
产品别名
479413-70-2
AUDA
12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H40N2O3 |
| Molecular weight | 392.58 |
| MDL number | MFCD12912267 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825206 |
| NACRES | NA.77 |
| Application【应用】 | AUDA may be used in soluble epoxide hydrolase-mediated cell signaling studies. AUDA has been used in the inhibition of epoxide hydrolase in human macrophages and in inhibition of tumor necrosis factor α (TNF-α)- induced phosphorylation in human aortic smooth muscle cells. |
| Biochem/physiol Actions【生化/生理作用】 | Inhibition of soluble epoxide hydrolase by AUDA inhibits the metabolism of epoxyeicosatrienoic acids (EETs) and protects end-organs against the damaging effects of salt-sensitive hypertension. AUDA also renders protection against myocardial ischemia-reperfusion injury and cerebral ischemia. AUDA is a potent inhibitor of soluble epoxide hydrolase |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: ≥10 mg/mL at warmed to 60 ℃ |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC(=O)CCCCCCCCCCCNC(=O)NC12C[C@@H]3C[C@@H](C[C@@H](C3)C1)C2 |
| InChI | 1S/C23H40N2O3/c26-21(27)10-8-6-4-2-1-3-5-7-9-11-24-22(28)25-23-15-18-12-19(16-23)14-20(13-18)17-23/h18-20H,1-17H2,(H,26,27)(H2,24,25,28)/t18-,19+,20-,23- |
| InChI key | XLGSEOAVLVTJDH-UKBVAGSOSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
