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Bisindolylmaleimide IV

产品编号:3415360
规格:≥98% (TLC), solid
CAS NO:119139-23-0
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
34153601 MG1086
产品别名

119139-23-0

Bisindolylmaleimide IV

Ro 31-6233

基本信息
Empirical Formula【经验(实验)分子式】
C20H13N3O2
Molecular weight
327.34
MDL number
MFCD00236432
PubChem Substance ID【PubChem化学物质编号】
24891709
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Bisindolylmaleimides (BIM) comprises a group of 11 compounds from BIM-I to BIM-XI. BIMs act as an inhibitor of protein kinase C (PKC). They are derived from staurosporine. BIM IX due to its proapoptotic functionality could be useful in targeting tumor proliferation.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
synthetic (organic)
Assay【测定】
≥98% (TLC)
form【形式】
solid
color【颜色】
dark red
solubility【溶解性】
DMSO: soluble
methanol: soluble
storage temp.【储存温度】
−20℃
SMILES string
O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c4c[nH]c5ccccc45
InChI
1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
InChI key
DQYBRTASHMYDJG-UHFFFAOYSA-N
Gene Information
human ... CDK2(1017), EGFR(1956)
rat ... Prkca(24680)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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