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BL-1249
产品别名
18200-13-0
BL-1249
(5,6,7,8-Tetrahydro-naphthalen-1-yl)-[2-(1H-tetrazol-5-yl)-phenyl]-amine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H17N5 |
| Molecular weight | 291.35 |
| MDL number | MFCD08276915 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724415 |
| NACRES | NA.77 |
| General description【一般描述】 | BL-1249 is a non-steroid anti-inflammatory drug and an inhibitor of the cyclooxygenase (COX) enzyme. |
| Application【应用】 | BL-1249 has been used:
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| Biochem/physiol Actions【生化/生理作用】 | BL-1249 also activates TWIK related potassium channel 2 (TREK2). It interacts with K2P channel at the negatively charged activator site and modulates channel opening. BL-1249 is a putative activator of potassium TREK-1 channel. |
| Features and Benefits【特点和优势】 | This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | pink to brown |
| solubility【溶解性】 | DMSO: ~17.5 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | C1CCc2c(C1)cccc2Nc3ccccc3-c4nnn[nH]4 |
| InChI | 1S/C17H17N5/c1-2-8-13-12(6-1)7-5-11-15(13)18-16-10-4-3-9-14(16)17-19-21-22-20-17/h3-5,7,9-11,18H,1-2,6,8H2,(H,19,20,21,22) |
| InChI key | YYNRZIFBTOUICE-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 - H413 |
| Precautionary Statements | P273 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
