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BNS-22
产品别名
1151668-24-4
BNS-22
8-[(3,4-Dihydro-2H-quinolin-1-yl)carbonyl]-5,7-dimethoxy-4-propyl-2H-chromen-2-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H25NO5 |
| Molecular weight | 407.46 |
| MDL number | MFCD22628799 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824719 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | BNS-22 is a derivative of natural product GUT-70 isolated from the stem bark of Calophyllum brasiliense exhibits antiproliferative activity against human cancer cells. It appears that BNS-22 is a specific DNA-topoisomerase II (TOPO2) catalytic inhibitor. BNS-22 does not induce DNA damage. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL (clear solution; warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COC1=C2C(OC(C=C2CCC)=O)=C(C(N3C(C=CC=C4)=C4CCC3)=O)C(OC)=C1 |
| InChI | 1S/C24H25NO5/c1-4-8-16-13-20(26)30-23-21(16)18(28-2)14-19(29-3)22(23)24(27)25-12-7-10-15-9-5-6-11-17(15)25/h5-6,9,11,13-14H,4,7-8,10,12H2,1-3H3 |
| InChI key | LRPUQCTZOSTSGL-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
