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Boc-Asp(OMe)-fluoromethyl ketone
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3415964 | 3 MG | 9580 |
产品别名
187389-53-3
Boc-Asp(OMe)-fluoromethyl ketone
Boc-
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H18NO5F |
| Molecular weight | 263.26 |
| MDL number | MFCD03453073 |
| PubChem Substance ID【PubChem化学物质编号】 | 329773206 |
| NACRES | NA.77 |
| Application【应用】 | Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus proliferation in chorion cells , as a component of the transplantation medium for the transplantation of human embryonic stem cells (ESC)-derived medial ganglionic eminence (MGE) cells into hippocampus of mice , as a protease inhibitor to study its effects on cell death in parasites . |
| Biochem/physiol Actions【生化/生理作用】 | Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥90% (TLC) |
| form【形式】 | solid |
| solubility【溶解性】 | DMF: soluble |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | COC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)CF |
| InChI | 1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1 |
| InChI key | MXOOUCRHWJYCAL-ZETCQYMHSA-N |
| packaging【包装】 | 3 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
