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Bradykinin Fragment 1-5
产品别名
23815-89-6
Bradykinin Fragment 1-5
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H40N8O6 |
| Molecular weight | 572.66 |
| MDL number | MFCD00076260 |
| PubChem Substance ID【PubChem化学物质编号】 | 24891591 |
| NACRES | NA.32 |
| Amino Acid Sequence | Arg-Pro-Pro-Gly-Phe |
| Biochem/physiol Actions【生化/生理作用】 | The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥97% (HPLC) |
| UniProt accession no.【UniProt登记号】 | P01042 |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(O)=O |
| InChI | 1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9-16,28H2,(H,32,37)(H,33,36)(H,40,41)(H4,29,30,31) |
| InChI key | USSUMSBPLJWFSZ-UHFFFAOYSA-N |
| Gene Information | human ... KNG1 (includes EG:3827)(3827) |
| packaging【包装】 | Bottomless glass bottle. Contents are inside inserted fused cone. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
