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C5a (His-Tag) from mouse
| 产品编号： | 3421454 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| CAS NO： | 80295-54-1 |
| 包装规格： | 20 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
80295-54-1
C5a (His-Tag) from mouse
Complement C5a
基本信息
| MDL number | MFCD00130842 |
| NACRES | NA.32 |
| General description【一般描述】 | Mouse complement C5a is a 77-amino acid peptide generated during complement activation from the α-chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat C5a, respectively. The 9 kDa mouse C5a protein expressed in E. coli contains a N-terminal His-Tag sequence. |
| Biochem/physiol Actions【生化/生理作用】 | C5a binds to a signaling G-protein coupled receptor (GPCR) (C5aR/CD88), inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells. |
| Physical form【外形】 | Sterile filtered and Lyophilized without additives. |
| Reconstitution【重悬】 | Reconstitute to a concentration of 1.0 mg/mL in ice-cold water containing 2.5 mg/mL BSA. The solution should be aliquoted and immediately stored at -70℃. Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~9 kDa |
| packaging【包装】 | pkg of 20 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | NP_034536 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... C5a(15139) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
