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Caramiphen hydrochloride
产品别名
125-85-9
Caramiphen hydrochloride
Pentaphen
2-(Diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate hydrochloride
Panparnit
Parpanil
Caramiphenium chloride salt
G 2747
Pentaphene hydrochloride
Parpanit
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H27NO2 · HCl |
| Molecular weight | 325.87 |
| MDL number | MFCD00242608 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825324 |
| NACRES | NA.77 |
| Application【应用】 | Caramiphen hydrochloride has been used to test its inhibitory effect on voltage-gated Na+ currents using the patch-clamp method. |
| Biochem/physiol Actions【生化/生理作用】 | Caramiphen hydrochloride is non-narcotic and possesses many biological functionalities of being antitussive, anticonvulsive, and neuroprotective. It induces sensory block and displays less toxicity when compared to bupivacaine. The local anesthetic functionality of caramiphen is mediated by its inhibitory effect on voltage-gated Na+ currents. Caramiphen is an anti-muscarinic similar to atropine; muscarinic acetylcholine receptor antagonist. Caramiphen is commonly used as a cough suppresant, but is also administered for the treatment of Parkinson′s disease. The compound has also been shown to have anti-depressant properties that may involve inhibition of G protein-coupled inwardly rectifying potassium channel GIRK. |
| Features and Benefits【特点和优势】 | This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: ≥5 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.CCN(CC)CCOC(=O)C1(CCCC1)c2ccccc2 |
| InChI | 1S/C18H27NO2.ClH/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16;/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3;1H |
| InChI key | MUPNXGNOIBYHSG-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
