CD40Ligand/TRAP from mouse

NA.32

CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18 kDa soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant mouse CD40 Ligand is a soluble 18 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L.

Sterile filtered and then lyophilized from 10 mM Sodium Phosphate, pH 7.5 plus 0.1 M Arginine.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

mouse

expressed in E. coli

≥98% (HPLC)
≥98% (SDS-PAGE)

lyophilized

<0.1 μg/mL ED₅₀

~16.4 kDa

pkg of 25 μg

avoid repeated freeze/thaw cycles

endotoxin, tested

P27548

wet ice

−20℃

mouse ... Cd40lg(21947)