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氯-APB 氢溴酸盐
Chloro-APB hydrobromide
产品别名
80751-65-1
氯-APB 氢溴酸盐
Chloro-APB hydrobromide
6-Chloro-N-allyl-SKF-38393 hydrobromide
(±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
(±)-SKF-82958 hydrobromide
(±)-6-氯-7,8-二羟基-3-烯丙基-1-苯基-2,3,4,5-四氢-1H-3-苯并氮杂卓 氢溴酸盐
(±)-SKF-82958 氢溴酸盐
6-氯-N-烯丙基-SKF-38393 氢溴酸盐
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H20ClNO2 · HBr |
| Molecular weight | 410.73 |
| MDL number | MFCD00069235 |
| PubChem Substance ID【PubChem化学物质编号】 | 24277890 |
| NACRES | NA.77 |
| Application【应用】 | Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice. |
| Biochem/physiol Actions【生化/生理作用】 | Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats. |
| Caution【注意】 | 光敏性 |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | solid |
| color【颜色】 | tan |
| solubility【溶解性】 | H2O: 3.7 mg/mL aqueous base: unstable ethanol: soluble |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3 |
| InChI | 1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H |
| InChI key | WLXGFAVTAAQOFH-UHFFFAOYSA-N |
| Gene Information | human ... DRD1(1812) |
| packaging【包装】 | 5 mg in glass bottle 25, 100 mg in poly bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
