您的位置：首页 > 产品中心 > 1049741-81-2， Ciproxifan hydrochloride
Ciproxifan hydrochloride
| 产品编号： | 3426014 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 1049741-81-2 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
1049741-81-2
Ciproxifan hydrochloride
Cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxyl]phenyl]-methanone hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H18N2O2 · HCl |
| Molecular weight | 306.79 |
| MDL number | MFCD08705321 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724449 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ciproxifan belongs to a novel chemical series of histamine H3-receptor antagonists. In vitro, it behaved as a competitive antagonist at the H3 autoreceptor controlling 3H histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with 125I-iodoproxyfan. Ciproxifan appears to be an orally bioavailable, extremely potent and selective H3-receptor antagonist whose vigilance- and attention-promoting effects are promising for therapeutic applications in aging disorders. |
| Features and Benefits【特点和优势】 | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| storage condition【储存条件】 | desiccated under inert gas |
| color【颜色】 | off-white |
| solubility【溶解性】 | DMSO: 30 mg/mL water, high purity: 30 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.O=C(C1CC1)c2ccc(OCCCc3c[nH]cn3)cc2 |
| InChI | 1S/C16H18N2O2.ClH/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14;/h5-8,10-12H,1-4,9H2,(H,17,18);1H |
| InChI key | PWAPSKMHZQQTRJ-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
