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克立马丁 富马酸盐
Clemastine fumarate salt
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3426614 | 100 MG | 1310 |
产品别名
14976-57-9
克立马丁 富马酸盐
Clemastine fumarate salt
1-Methyl-2-[2-(methyl-p-chlorodiphenylmethyloxy)ethyl]pyrrolidine fumarate salt
1-Methyl-2-[2-(α-methyl-p-chlorobenzhydryloxy)ethyl]pyrrolidine fumarate salt
(2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine fumarate salt
(+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt
Meclastine fumarate salt
Mecloprodine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H26ClNO · C4H4O4 |
| Molecular weight | 459.96 |
| EC number【EC 号】 | 239-055-2 |
| MDL number | MFCD00137486 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824727 |
| NACRES | NA.77 |
| General description【一般描述】 | Clemastine fumarate is used to treat multiple sclerosis, sneezing and rhinorrhea linked to common cold. It stimulates oligodendrocyte progenitor cell (OPC) differentiation and myelination. |
| Application【应用】 | Clemastine fumarate salt has been used as a stimulator of rodent oligodendrocyte generation and myelination in vitro and in vivo. |
| Biochem/physiol Actions【生化/生理作用】 | Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic that also has antipruritic activity. |
| Features and Benefits【特点和优势】 | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D +15 to +25°, c = 1 in methanol |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 5 mg/mL (clear solution; warmed) |
| storage temp.【储存温度】 | room temp |
| SMILES string | OC(=O)\C=C\C(O)=O.CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3 |
| InChI | 1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1 |
| InChI key | PMGQWSIVQFOFOQ-YKVZVUFRSA-N |
| Gene Information | human ... HRH1(3269) |
| packaging【包装】 | 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
