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Cathepsin B Inhibitor II-Calbiochem

产品编号:4061655
规格:The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40616551 MG1940
产品别名

Cathepsin B Inhibitor II-Calbiochem

Ac-LVK-CHO

基本信息
Empirical Formula【经验(实验)分子式】
C19H36N4O4
Molecular weight
384.51
General description【一般描述】
Note: this peptide forms cyclic isomers.
Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) than of leupeptin (IC50 = 310 nM). Note: this peptide forms cyclic isomers.
A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) compared to leupeptin (IC50 = 310 nM).
Biochem/physiol Actions【生化/生理作用】
Product does not compete with ATP.
Primary Target
cathepsin B
Reversible: no
Target IC50: 4 nM against cathepsin B
Cell permeable: no
Warning【警告】
Toxicity: Standard Handling (A)
Sequence【序列】
Ac-Leu-Val-lysinal
Reconstitution【重悬】
Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.
Other Notes【其他说明】
McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥95% (HPLC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
color【颜色】
white
solubility【溶解性】
water: 1 mg/mL
shipped in【运输】
ambient
storage temp.【储存温度】
−70℃
packaging【包装】
1 mg in Plastic ampoule
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 1
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