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FURA 2/AM in Solution-CAS 108964-32-5-Calbiochem
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4061675 | 1 ML | 3570 |
产品别名
108964-32-5
FURA 2/AM in Solution-CAS 108964-32-5-Calbiochem
基本信息
| Empirical Formula【经验(实验)分子式】 | C44H47N3O24 |
| Molecular weight | 1001.85 |
| MDL number | MFCD00036976 |
| General description【一般描述】 | Cell-permeable ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30X greater fluorescence intensity that QUIN 2 (Cat. No. 551826). This probe has been used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm). |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Irritant (B) |
| Physical form【外形】 | A 1 mM solution of FURA 2/AM (Cat. No. 344905) in anhydrous DMSO. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). Store frozen under an inert atmosphere. |
| Other Notes【其他说明】 | Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292. Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol.47, 226. Schwartz, Y., et al. 1992. Endocrinology131, 772. Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol.24, 937. Janconi, M.E., et al. 1990. J. Cell Biol.110, 1555. Tsien, R.Y. 1980. Biochemistry19, 2396. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| fluorescence【荧光】 | λex 335 nm (high) λex 362 nm (low) λem 505 nm (high) λem 512 nm (low) |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C44H47N3O24/c1-25-7-8-32(46(16-38(53)65-20-60-26(2)48)17-39(54)66-21-61-27(3)49)35(13-25)58-11-12-59-42-31-14-36(43-45-15-37(71-43)44(57)69-24-64-30(6)52)70-34(31)10-9-33(42)47(18-40(55)67-22-62-28(4)50)19-41(56)68-23-63-29(5)51/h7-10,13-15H,11-12,16-24H2,1-6H3 |
| InChI key | UTBYGIDPBQOHNT-UHFFFAOYSA-N |
| packaging【包装】 | 1 ml in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
| Flash Point(F)【闪点(F)】 | 188.6 °F - (Dimethylsulfoxide) |
| Flash Point(C)【闪点(C)】 | 87 ℃ - (Dimethylsulfoxide) |
