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InSolution LY 294002-CAS 154447-36-6-Calbiochem

产品编号:4061704
规格:InSolution LY 294002, CAS 154447-36-6, is a 10 mM solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4 μM).
CAS NO:154447-36-6
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40617041 MG1500
产品别名

154447-36-6

InSolution LY 294002-CAS 154447-36-6-Calbiochem

2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, BRD2 Inhibitor IV, BRD3 Inhibitor III, BRD4 Inhibitor IV

基本信息
Empirical Formula【经验(实验)分子式】
C19H17NO3
Molecular weight
307.34
Biochem/physiol Actions【生化/生理作用】
Cell permeable: yes
Primary Target
phosphatidylinositol 3-kinase
Target IC50: 1.4 µM against phosphatidylinositol 3-kinase
Product competes with ATP.
Reversible: yes
Warning【警告】
Toxicity: Irritant (B)
Physical form【外形】
A 10 mM (1 mg/325 µl) solution of LY 294002 (Cat. No. 440202) in DMSO.
Reconstitution【重悬】
Following initial thaw, aliquot and freeze (-20°C).
Other Notes【其他说明】
Dittman, A., et al. 2013. ACS Chem. Biol.9, 495.
Baumann, P., and West, S.C. 1998. Proc. Natl. Acad. Sci. USA95, 14066.
Cardone, M.H., et al. 1998. Science282, 1318.
Vlahos, C.J., et al. 1995. J. Immunol.154, 2413.
Yano, H., et al. 1995. Biochem. J.312, 145.
Vlahos, C.J., et al. 1994. J. Biol. Chem.269, 5241.



Selected Citations
Lee, J., et al. 2009. Cell Stem Cell5, 76.


Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
liquid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
protect from light
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
InChI
1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
InChI key
CZQHHVNHHHRRDU-UHFFFAOYSA-N
packaging【包装】
1 mg in Plastic ampoule
Packaged under inert gas
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)【闪点(F)】
188.6 °F - (refers to pure substance)
Flash Point(C)【闪点(C)】
87 ℃ - (refers to pure substance)
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