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VEGF Inhibitor, Flt2-11-Calbiochem
| 产品编号： | 4061765 |
| 规格： | The VEGF Inhibitor, Flt2-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
VEGF Inhibitor, Flt2-11-Calbiochem
NITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I
基本信息
| Empirical Formula【经验(实验)分子式】 | C61H104N14O15 |
| Molecular weight | 1273.56 |
| General description【一般描述】 | An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is shown to inhibit angiogenesis in chick chorioallantoic membrane and inhibits VEGF-induced vascular permeability. Neither binds to vascular endothelial growth factor (VEGF) nor inhibits its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution. An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is reported to inhibit angiogenesis in chick chorioallantoic membrane and VEGF-induced vascular permeability. Does not bind to vascular endothelial growth factor (VEGF) nor inhibit its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target VEGF Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | H-Asn-Ile-Thr-Val-Thr-Leu-Lys-Lys-Phe-Pro-Leu-OH |
| Other Notes【其他说明】 | Tan, D.C., et al. 2001. FEBS Lett.494, 150. |
| Legal Information【法律信息】 | Sold under license of U.S. Patent 6,200,954. CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | lyophilized solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) |
| color【颜色】 | white |
| solubility【溶解性】 | acetonitrile: 20% DMSO: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 1 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
