Li-Li Auxiliary

C₁₅H₁₃N₃O₄S

331.35

Li-Li auxiliary assists the direct meta-C–H olefination and acetoxylation of benzoic acids through a nitrile-based sulfonamide template under mild conditions. The expansion of substrate scope regardless of substitution patterns and steric biases will enable the wide adoption of this protocol to the synthesis of drug molecules and natural products, of which benzoic acids are significant motifs.

Pd(II)-catalysed meta-C–H functionalizations of benzoic acid derivatives

100

≥95%

powder or crystals

reagent type: ligand
reaction type: C-H Activation

1 g in glass insert

13 - Non Combustible Solids

WGK 3