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来自肝脏的微粒体，合并
Microsomes from Liver, Pooled
产品别名
来自肝脏的微粒体，合并
Microsomes from Liver, Pooled
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse (CD-1) |
| Assay【测定】 | ~10 mg per vial |
| form【形式】 | liquid |
| UniProt accession no.【UniProt登记号】 | Q91VS7 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | mouse ... Mgst1(56615) |
基本信息
| General description【一般描述】 | Microsomes are the fraction of "submicroscopic” particles isolated from homogenates of liver and other tissues. Microsomes are rich in ribonucleic acid (RNA). |
| Application【应用】 | Microsomes from Liver, Pooled has been used in cell survival and mutation assays in Escherichia coli. Microsomes from Liver, Pooled has been also been used to study the metabolic stability of antitumor agents and tunicamycin. |
| Biochem/physiol Actions【生化/生理作用】 | Microsomes might act as cell organelles and are actively involved in protein synthesis. Carbon monoxide-binding pigment of microsomes, named P-450, is an integral element of mixed function oxidase systems involved in the oxidative demethylation and hydroxylation of drugs and steroids. Murine liver microsomes plays a crucial role in degradation of small antimicrobial β2,2-amino acid derivatives. 肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。 |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
