Anti-phospho-Rsk1 (p90^rsk) (pSer³⁸¹) antibody produced in rabbit

MFCD02097169

NA.44

Rsk1 is a ubiquitously expressed, mitogen-activated protein that belongs to the serine/threonine protein kinase family. It has a pivotal role in facilitating MEK-MAP kinase cell survival signaling and supressing pro-apoptotic function of BAD by its phosphorylation. Anti-phospho-Rsk1 (p90rsk) (pSer381) antibody can be used to detect Rsk1 when phosphorylated at phosphoserine 381. It can also be used in immunoprecipitation (diluted 1:200). Rabbit anti-phospho-Rsk1 (p90rsk) (pSer381) antibody reacts specifically with phosphorylated Rsk1 and not with nonphosphorylated Rsk1. The product has also specificity for Rsk1 of rat, mouse and human.

Synthetic phospho-Ser381 peptide corresponding to residues around Ser381 of human (p90rsk) conjugated to KLH.

Anti-phospho-Rsk1 (p90rsk) (pSer381) antibody can be used in western blotting (diluted 1:1000) using TPA-treated 293 cell extract. It can also be used in immunocytochemistry (diluted 1:2000).

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous glycerol solution

human, mouse, rat

immunocytochemistry: 1:2,000
immunoprecipitation (IP): 1:200
western blot (chemiluminescent): 1:1,000 using TPA-treated 293 cell extract

Q15418

wet ice

−20℃

human ... RPS6KA1(6195)
mouse ... Rps6ka1(20111)
rat ... Rps6ka1(81771)

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