Anti-phospho-Tyk2 (pTyr^1054/1055) antibody produced in rabbit

MFCD02097177

NA.44

Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by
receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-a and β. Following ligand binding,
Tyk2 is activated by phosphorylation of Tyr1054 and/or Tyr1055. Tyk2 is required for the tyrosine phosphoryla-
tion of Stat3 in the IFN-β signaling cascade.

Detects human Tyk2 only when phosphorylated at Tyr^1054/1055.

synthetic phospho-Tyr^1054/1055 peptide corresponding to residues around Tyr^1054/1055 of human Tyk2.

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous glycerol solution

134 kDa

human

western blot: 1:1000

P29597

wet ice

−20℃

human ... TYK2(7297)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 1