Leucinostatin A+B mixture

200

(Paecilomyces lilacinus)

≥95% (mixture of Leucinostatin A+B, HPLC)

powder

DMF: 10 mg/mL
DMSO: 10 mg/mL
ethanol: 10 mg/mL
methanol: 10 mg/mL

−20℃

Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus. Leucinostatins display broad bio-activity against gram-positive bacteria, fungi, plants and tumor cell lines. They play a role as uncouplers in the inner mitochondria membrane and inhibit mitochondrial ATP synthesis. Recently, interest in Leucinostatins has focused on other aspects such as understanding their activity: insulin-like growth factor I regulators, ionophore, inhibitors of cell surface expression of viral glycoproteins and their potent in vitro and in vivo anti-trypanosomal activity.

Mixture of Leucinostatin A (Cas# 76600-38-9 / MF: C₆₂H₁₁₁N₁₁O₁₃) and Leucinostatin B (Cas# 76663-52-0 / MF: C₆₁H₁₀₉N₁₁O₁₃).

Stable at −20 ℃ for at least 2 years.

13 - Non Combustible Solids

WGK 3