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诺氟沙星
Norfloxacin
| 产品编号： | 4063818 |
| 规格： | Pharmaceutical Secondary Standard; Certified Reference Material |
| CAS NO： | 70458-96-7 |
| 包装规格： | 1 G |
| 产品类别： | 进口试剂 |
| 品牌： | Supelco |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4063818 | 1 G | 2630 |
产品别名
70458-96-7
诺氟沙星
Norfloxacin
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid
1-乙基-6-氟-1,4-二氢-4-氧代-7-哌嗪-3-喹啉羧酸
1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H18FN3O3 |
| Molecular weight | 319.33 |
| EC number【EC 号】 | 274-614-4 |
| MDL number | MFCD00079532 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823510 |
| NACRES | NA.24 |
| General description【一般描述】 | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Norfloxacin is a synthetic broad-spectrum antibacterial drug that is effective against various gram positive and gram negative bacteria. Its major application is in the treatment of urinary tract infections. |
| Application【应用】 | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Norfloxacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and serum samples by high performance liquid chromatography (HPLC) and spectrophotometric methods. |
| Biochem/physiol Actions【生化/生理作用】 | 诺氟沙星通过干扰 ATP 诱导转换 DNA 与 DNA 旋转酶(拓扑异构酶)复合物的结构转换而阻断 DNA 复制。 操作方式：抑制细菌 DNA 复制 抗菌谱：革兰阴性菌；对革兰阳性菌疗效较差 |
| Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAC2802 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
| Quality Level【质量水平】 | 300 |
| grade【等级】 | certified reference material pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| packaging【包装】 | pkg of 1 g |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| application(s) | pharmaceutical (small molecule) |
| format【格式】 | neat |
| pharmacopeia traceability【药典可追溯性】 | traceable to BP 670 traceable to PhEur N1230000 traceable to USP 1471506 |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3 |
| InChI | 1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23) |
| InChI key | OGJPXUAPXNRGGI-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
