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(R)-FTY720-OMe
| 产品编号： | 4064079 |
| 规格： | (R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol, neat oil |
| CAS NO： | 1382486-90-9 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1382486-90-9
(R)-FTY720-OMe
(R)-FTY720-methyl ether; ROME
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H35NO2 |
| Molecular weight | 321.50 |
| NACRES | NA.25 |
| General description【一般描述】 | (R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity. (R)-FTY720-OMe is the analogue of FTY720. |
| Biochem/physiol Actions【生化/生理作用】 | (R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential. |
产品性质
| Assay【测定】 | >99% (TLC) |
| manufacturer/tradename | Avanti Polar Lipids 857392O |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (857392O-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
