C12-NBD Ceramide

C₃₆H₆₁N₅O₆

659.90

NA.25

C12-NBD ceramide is suitable for its use:

• as a substrate to measure the activity of acid, alkaline and neutral ceramidases
• in in vitro ceramidase activity assay
• in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

>99% (TLC)

Avanti Polar Lipids 810211C

1 mg/mL (810211C-1mg)

dry ice

−20℃

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

GHS06,GHS08

Danger

H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372

P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Central nervous system

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK 3