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人双调蛋白ELISA试剂盒
Human Amphiregulin ELISA Kit
| 产品编号： | 4067148 |
| 规格： | for serum, plasma, cell culture supernatant and urine |
| 包装规格： | 1 KIT |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
人双调蛋白ELISA试剂盒
Human Amphiregulin ELISA Kit
AR
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | The Human Amphiregulin (AR) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human AR in serum, plasma, cell culture supernatants and urine. The AREG (amphiregulin) gene codes for a shedding ectodomain, derived from a transmembrane precursor of 252 amino acids. The encoded protein is released into blood or cellular vicinity through autocrine and paracrine. Areg is predominantly expressed in epithelial, mesenchymal cells and also by active immune cells. The AREG gene is mapped to human chromosome 4q13.3. |
| Immunogen【免疫原】 | Recombinant Human Amphiregulin |
| Application【应用】 | Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA) Human Amphiregulin ELISA Kit has been used to estimate the plasma concentration of amphiregulin by ELISA. |
| Biochem/physiol Actions【生化/生理作用】 | Areg (amphiregulin) stimulates growth-signaling pathways via EGF (epidermal growth factor) receptors. Areg participates in the organogenesis of mammary gland. It is regarded as a pro-oncogenic factor and contributes to tumor progression. Upregulation of the AREG gene is observed in cancer and resists chemotherapy. AREG reduces E-cadherin expression in order to promote invasion and progression of ovarian cancer. |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Components【组分】 | 组份可单独销售 RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1) RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1) RABSTOP3 ELISA Stop Solution (Item I) RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) RABWASH4 20X Wash Buffer (Item B) |
产品性质
| species reactivity | human |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable capture ELISA: suitable |
| input | sample type serum sample type cell culture supernatant(s) sample type plasma sample type urine |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 10 pg/mL standard curve range: 16.46-4000 pg/mL |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... AREG(374) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
