InnoBridge ELISA试剂盒

NA.32

A Protein Conformational Array (PCA) in a sandwich ELISA format where the plate is coated with a panel of antibodies raised against peptides derived from the full length protein sequence of seven commercial monoclonal antibody biologic drugs (Biologics). Taken individually, each of these antibodies is strongly antigenic to the peptide sequence that was used in its production. However, when these peptides are incorporated into a full length correctly folded protein, the antigenicity of many of them is masked by the three dimensional structure of the protein and only a limited number of the antibodies respond. The result is a histogram which can be likened to a ‘fingerprint′ for any given monoclonal antibody. Once that ‘fingerprint′ is established, then any changes that occur in that mAb during purification or other manipulations will likely expose a new antigenic site which can be detected by the antibodies on the plate.

For research use only. Not for use in diagnostic procedures.

IgG fraction of antiserum

human (Human IgG)

wet ice

−20℃

GHS05

Warning

H290 - H315 - H319

P305 + P351 + P338

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

8A - Combustible, corrosive hazardous materials