小鼠促红细胞生成素EPO ELISA试剂盒

NA.32

This ELISA antibody pair detects Mouse Erythropoietin (EPO)

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Erythropoietin (EPO) is a glycoprotein hormone which is essential for the proliferation of erythropoietic progenitors to produce red blood cells (RBCs). Peritubular fibroblast in kidney cortex is the primary site for EPO production in adults, though spleen, bone marrow and liver contribute to the production. In fetus, liver is the primary site for EPO production. Additionally, EPO functions in some cytoprotective activities like, antiapoptotic, antioxidant, and anti-inflammatory responses. Hypoxia inducible factors upregulate EPO expression. EPO expression increases with decreased hemoglobin concentration in few cases of anemia. Decreased production of EPO is the cause of anemia in chronic kidney diseases. Circulating endogenous antibodies to EPO (anti-EPO) is the cause of anemia in multiple diseases like human immunodeficiency virus (HIV) infection, hepatitis C virus infection, systemic lupus erythematosus. Gain-of-function polymorphism in EPO causes familial erythrocytosis.

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

mouse

kit of 96 wells (12 strips x 8 wells)

ELISA: suitable

sample type serum sample(s)
sample type cell culture supernatant(s)
sample type plasma

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/ml

colorimetric

wet ice

−20℃

mouse ... Epo(13856)

GHS05

Warning

H290

P234 - P390

Met. Corr. 1

8A - Combustible, corrosive hazardous materials

WGK 3