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小鼠Gremlin-1 ELISA试剂盒
Mouse Gremlin-1 ELISA Kit
产品编号: | 4068100 |
规格: | for cell culture supernatants, plasma, and serum samples |
包装规格: | 96 WELLS |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
小鼠Gremlin-1 ELISA试剂盒
Mouse Gremlin-1 ELISA Kit
基本信息
NACRES | NA.32 |
General description【一般描述】 | Gremlin-1 (GREM1) is part of the secreted, cysteine knot DAN family of bone morphogenetic protein antagonists. It has a molecular weight of 24–26kDa. |
Application【应用】 | For research use only. Not for use in diagnostic procedures. Please refer to the attached Protocolfor details. |
Biochem/physiol Actions【生化/生理作用】 | Gremlin-1 (GREM1) has a role in embryogenesis. It also has a role in cell functions during development. GREM1 acts as an antagonist of bone morphogenetic proteins (BMP). The protein influences chondrogenesis, outgrowth and apoptosis in limb bud development and has a role in kidney formation. It inhibits the activity of BMP2 and BMP4. GREM1 is involved in angiogenesis, bone formation, bone mass and pulmonary hypertension. Knockout of this gene in mice leads to developmental abnormalities. |
Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
产品性质
species reactivity | mouse |
packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
technique(s) | ELISA: suitable |
input | sample type plasma sample type serum sample(s) sample type cell culture supernatant(s) |
assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.8 ng/ml |
Detection Method | colorimetric |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Grem1(23892) |
安全信息
Pictograms【象形图】 | GHS05 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H290 |
Precautionary Statements | P234 - P390 |
Hazard Classifications【危险分类】 | Met. Corr. 1 |
Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
WGK | WGK 3 |