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7α,27-dihydroxy-4-cholesten-3-one
产品别名
192187-67-0
7α,27-dihydroxy-4-cholesten-3-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H44O3 |
| Molecular weight | 416.64 |
| General description【一般描述】 | 7α,27-dihydroxy-4-cholesten-3-one synthesized by the hydroxylation of 27-hydroxycholesterol in the presence of the enzyme cholesterol 7 α-hydroxylase (CYP7A1) and is catabolized to bile acid. 7α,27-dihydroxy-4-cholesten-3-one is present majorly in fibroblasts and its conversion from cholesterol occurs in extrahepatic tissues. |
| Application【应用】 | 7α,27-dihydroxy-4-cholesten-3-one may be used as a ligand to test its effect on Epstein-Barr virus-induced molecule 2 (EB12) activation in guanosine 5′-O-(3-thio)triphosphate ([35S] GTPγS) binding assay. |
| Biochem/physiol Actions【生化/生理作用】 | 7α,27-dihydroxy-4-cholesten-3-one is a suppressor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700023P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700023P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
