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抗 大鼠 IgM(μ-链特异性)- 过氧化物酶 山羊抗
Anti-Rat IgM (μ-chain specific)-Peroxidase antibody produced in goat
| 产品编号： | 4070699 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
抗 大鼠 IgM(μ-链特异性)- 过氧化物酶 山羊抗
Anti-Rat IgM (μ-chain specific)-Peroxidase antibody produced in goat
HRP
基本信息
| NACRES | NA.46 |
| General description【一般描述】 | Immunoglobulin M (IgM) exists as a pentamer in the serum and has a high molecular weight. Monomeric IgM has a molecular weight of 190kDa. The pentameric IgM consists of ten μ-heavy chains, ten light chains and a single J-chain which are linked by disulphide bonds. The μ-chain consists of five domains- VH, Cμ1, Cμ2, Cμ3 and Cμ4. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as Fragment antigen binding (Fab) fragments. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. The heavy chains of IgM contain an extra C domain that replaces the hinge region present between Fab and Fc. IgM is the first antibody to be produced during an immune response. |
| Specificity【特异性】 | This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgM coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Goat Serum, Rat IgM and Rat Serum. Specificity was confirmed by ELISA at less than 1% cross reactivity against other Rat heavy or light chain isotypes. |
| Immunogen【免疫原】 | Rat IgM mu heavy chain |
| Physical properties【物理属性】 | Antibody format: IgG |
| Physical form【外形】 | Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free |
| Reconstitution【重悬】 | Reconstitute with 1.0 mL deionized water (or equivalent). |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | peroxidase conjugate |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | secondary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | rat |
| technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H317 |
| Precautionary Statements | P280 |
| Hazard Classifications【危险分类】 | Skin Sens. 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
