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c 反应蛋白 人

C Reactive Protein human
产品编号:4070939
规格:recombinant, expressed in E. coli, liquid
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40709391 MG9410
产品别名

c 反应蛋白 人

C Reactive Protein human

CRP

基本信息
MDL number
MFCD00130690
NACRES
NA.32
General description【一般描述】
C-reactive protein (CRP), a homopentameric acute-phase inflammatory protein, is produced mainly in liver hepatocytes. This highly conserved plasma protein is also produced by smooth muscle cells, macrophages, endothelial cells, lymphocytes, and adipocytes. It belongs to the pentraxin family.
Application【应用】
C Reactive Protein human has been used:
  • as a component in differentiation medium to study the effects of C-reactive protein (CRP) on the size of myotubes and myotube mixed protein synthesis (MPS)
  • to study the influence of serum CRP level from elderly on endothelial cell proliferation in human umbilical vein endothelial cells (HUVEC)
  • to study the roles and connections of nicotine, monocytic interleukin 6 (IL-6), α7 nicotinic acetylcholine receptor (α7-nAChR), and CRP in the development of coronary artery spasm (CAS)

Biochem/physiol Actions【生化/生理作用】
C-reactive protein (CRP) plays a key role in the complement pathway, apoptosis, phagocytosis, nitric oxide (NO) release, and the production of interleukin-6 and tumor necrosis factor-α. It participates in the uptake of low-density lipoprotein in macrophages. CRP levels are elevated in people suffering from appendicitis, cholecystitis, pancreatitis, and meningitis. It plays a vital role in the pathophysiology of cardiovascular disease. Hence it is used as a marker of infection and cardiovascular events.
C-反应蛋白 (CRP) 是一种能沉淀肺炎球菌细胞壁中 C-多糖的蛋白质。CRP 被广泛用作炎症状态的临床标志物,因为在炎症反应的急性期,肝细胞产生的 CRP 增加。
Analysis Note【分析说明】
一种高度纯化的蛋白质,通过发酵过程使用转基因 大肠杆菌制成。
产品性质
Quality Level【质量水平】
200
recombinant【重组】
expressed in E. coli
form【形式】
liquid
mol wt【分子量】
23 kDa
bp
~100 ℃
UniProt accession no.【UniProt登记号】
P02741
storage temp.【储存温度】
2-8℃
Gene Information
human ... CRP(1401)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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