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campesterol-d6
产品别名
2260669-13-2
campesterol-d6
26,27-hexadeuteriocampest-5-en-3β-ol; 111018
基本信息
| Empirical Formula【经验(实验)分子式】 | C28H42D6O |
| Molecular weight | 406.72 |
| NACRES | NA.25 |
| General description【一般描述】 | Campesterol-d6 is the deuterated form of campesterol. It is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure. It is not synthesized in mammanls and is diet derived |
| Application【应用】 | Campesterol-d6 has been used as a deuterium-labeled internal standard in gas chromatography (GC)–triple quadrupole mass spectrometry and liquid chromatography-high resolution mass spectrometry (LC-HRMS). |
| Biochem/physiol Actions【生化/生理作用】 | Campesterol reduces the levels of chylomicron. The d6-campesterol along with d6-sitosterol and d6-cholesterol has been used in the transport blood-brain barrier studies in human brain endothelial hCMEC/D3 monolayer cells. Campesterol is a biomarker for tracking cholesterol synthesis and absorption. Campesterol like cholesterol is catabolized by intestinal microbes. It possess chemopreventive functionality prostate and breast tumors. Campesterol also has antiangiogenic property and may be useful in treating disorders related to angiogenesis. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700092P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700092P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
