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人碳酸酐酶IX ELISA试剂盒
Human Carbonic Anhydrase IX ELISA Kit
| 产品编号： | 4071761 |
| 规格： | for serum, plasma, cell culture supernatant and urine |
| 包装规格： | 1 KIT |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
人碳酸酐酶IX ELISA试剂盒
Human Carbonic Anhydrase IX ELISA Kit
CA9
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Carbonic anhydrase IX (CA9) belongs to the zinc-containing metalloenzymes family. The protein is encoded by the gene mapped to human chromosome 9p. The encoded protein is localized on cell membrane and is characterized with an N-terminal proteoglycan-like domain (PG), a CA catalytic domain (CA), a transmembrane helical segment and a short intra-cytoplasmic tail. CA9 is expressed at very low levels in normal tissues (mostly in gastrointestinal tract), but it is expressed at high level in various cancer tissues, such as renal, lung, cervical, ovarian, esophageal and breast cancer. The Human CA-IX (Carbonic Anhydrase IX) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CA-IX in serum, plasma, cell culture supernatants and urine. |
| Immunogen【免疫原】 | Recombinant Human CA9 |
| Application【应用】 | 请参考Protocol了解详情。 |
| Biochem/physiol Actions【生化/生理作用】 | Carbonic anhydrase IX (CA9) aids in reversible hydration of carbon dioxide to carbonic acid and bicarbonate. CA9 functions as a promising biomarker for diagnosing clear cell renal cell carcinoma (ccRCC), tumor hypoxia and prostate cancer (PC). In addition to pH control, CA9 also plays a vital role in cell proliferation, adhesion and tumor invasion. |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Components【组分】 | 组份可单独销售 RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1) RABELADC ELISA 1X Assay/Sample Diluent Buffer C (Item L) RABSTOP3 ELISA Stop Solution (Item I) RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) RABWASH4 20X Wash Buffer (Item B) |
产品性质
| species reactivity | human |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable capture ELISA: suitable |
| input | sample type urine sample type cell culture supernatant(s) sample type plasma sample type serum |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.2 pg/mL standard curve range: 0.205-50 pg/mL |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CA9(768) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
