Human MMP-13 ELISA Kit

NA.32

The Human MMP-13 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-13 in serum, plasma, cell culture supernatants and urine.

Recombinant Human MMP13

请参考Protocol了解详情。

MMP13 (matrix metalloproteinase 13) functions against different types of ECM (extracellular matrix) components. It gets activated by and activates multiple MMPs and hence, has a central role in the MMP cascade. This protein is frequently expressed in colorectal cancer (CRC) and this expression is linked with poor survival in CRC. MMP13 expression is absent in normal breast tissue, but is present in breast carcinoma suggesting its role in tumorigenesis. The expression of this protein can serve as a marker for tumor invasiveness, as its expression is induced during metastasis of multiple types of cancers, including squamous cell carcinomas of the head and neck and this expression is usually linked to poor prognosis. Missense mutation in this gene results in the autosomal dominant disorder called Missouri type of human spondyloepimetaphyseal dysplasia (SEMDMO), which is characterized by abnormal growth and modeling of vertebrae and long bones.

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组份可单独销售
RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
RABSTOP3 ELISA Stop Solution (Item I)
RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH4 20X Wash Buffer (Item B)

human

kit of 96 wells (12 strips x 8 wells)

ELISA: suitable
capture ELISA: suitable

sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type urine

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 8.23-6000 pg/mL

colorimetric

wet ice

−20℃

human ... MMP13(4322)

GHS05

Warning

H290

P234 - P390

Met. Corr. 1

8A - Combustible, corrosive hazardous materials

WGK 3