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lathosterol-d7
| 产品编号： | 4072365 |
| 规格： | 5α-Cholest-7-en-3β-ol (25,26,26,26,27,27,27-d7), powder |
| CAS NO： | 2260669-10-9 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
2260669-10-9
lathosterol-d7
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H39D7O |
| Molecular weight | 393.70 |
| NACRES | NA.25 |
| General description【一般描述】 | Lathosterol is a metabolite of cholesterol present in human breast milk. Lathosterol is catabolized by lathosterol 5-desaturase to 7-dehydrocholesterol, which is a precursor of cholesterol. Lathosterol-d7 is a deuterated derivative of lathosterol. |
| Application【应用】 | Lathosterol-d7 has been used as an internal standard in gas chromatography-mass spectrometry (GC–MS) for the breast milk sterol quantification and in liquid chromatography high resolution mass spectrometry (LC–HRMS) analysis. |
| Biochem/physiol Actions【生化/生理作用】 | Lathosterol levels are direct indicators of cholesterol levels and aid in decoding metabolism defects. Elevated levels of lathosterol is implicated in cerebrotendinous xanthomatosis (CTX) and lathosterolosis. The inactivation of enzyme lathosterol 5-desaturase (SC5D) leads to accumulation of lathosterol in lathosterolosis pathology. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700056P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700056P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
