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MMK-1 trifluoroacetate
产品别名
271246-66-3
MMK-1 trifluoroacetate
L-Methionine, L-leucyl-L--glutamyl-L-seryl-L-isoleucyl-L-phenylalanyl-L-arginyl-L-seryl-L-leucyl-L-leucyl-L-phenylalanyl-L-arginyl-L-valyl-
LESIFRSLLFRVM trifluoroacetate
GTPL6240
MMK-1 TFA
Leu-Glu-Ser-Ile-Phe-Arg-Ser-Leu-Leu-Phe-Arg-Val-Met trifluoroacetate
基本信息
| Empirical Formula【经验(实验)分子式】 | C75H123N19O18S · xC2HF3O2 |
| Molecular weight | 1610.96 (free base basis) |
| Biochem/physiol Actions【生化/生理作用】 | MMK-1 is a potent and selective FPR2 (FPRL-1) agonist (Ca2+ flux EC50 <2 nM/FPR2 vs. >10 μM/FPR1 with respective HEK293 transfectants) and an effective calcium-mobilizing and chemotactic agent for human monocytes & neutrophils (1-1000 nM). MMK-1 increases pertussis toxin-sensitive inflammatory cytokines production in human monocyte cultures (50 ng/mL PT & 10 μM MMK-1), exerts anxiolytic-like activities in mice (100 pmol/mouse icv) and shows anti-alopecia efficacy in rats in vivo (100 mg/kg p.o. or 10 mg/kg i.p.). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | film or powder |
| color【颜色】 | white to beige |
| storage temp.【储存温度】 | −20℃ |
