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基质金属蛋白酶-3活性检试剂盒(荧光法)
MMP-3 Activity Fluorometric Assay Kit
产品别名
基质金属蛋白酶-3活性检试剂盒(荧光法)
MMP-3 Activity Fluorometric Assay Kit
基本信息
NACRES | NA.84 |
General description【一般描述】 | 基质金属蛋白酶-3(MMP-3,溶基质素-1)表现出的一些活性,使其成为良好的肿瘤启动子。与其他几种MMP相似,MMP-3作为癌症特异性基因,先后经过首次克隆和再次克隆。除了可以降解大量细胞外基质,MMP-3还能够激活明胶酶B、胶原酶和多种丝氨酸蛋白酶抑制剂。此外,它还能够释放大量细胞表面分子,包括E-钙粘素,一种已知可导致癌症发生的蛋白质。 |
Features and Benefits【特点和优势】 | Compatible with high-throughput handling systems. |
Principle【原理】 | Matrix metalloproteinase-3 (MMP-3) assay kit, MMP-3 hydrolyzes a specific FRET (fluorescence resonance energy transfer) substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically (lex = 325 nm/lem = 393 nm). The kit provides a rapid, simple, sensitive and reliable test, which can also be used as a high throughput assay of MMP-3 activity. The assay sensitivity is <50 mU. |
产品性质
Detection Method | fluorometric |
storage temp.【储存温度】 | −20℃ |
suitability【适用性】 | Suitable for measuring MMP-3 activity in various biological samples. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 3 |