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Arachidonic Acid-CAS 506-32-1-Calbiochem
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4073876 | 100 MG | 1790 | |||
| 4073876 | 1 G | 3640 |
产品别名
506-32-1
Arachidonic Acid-CAS 506-32-1-Calbiochem
cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H32O2 |
| Molecular weight | 304.47 |
| MDL number | MFCD00004417 |
| General description【一般描述】 | A cis-polyunsaturated fatty acid found in the plasma membrane. Major component of membrane phospholipids. Following its release by cellular phospholipases, it is enzymatically converted to a variety of inflammatory and vasoactive metabolites, such as prostaglandins (via the cyclooxygenase pathway), leukotrienes (via the lipoxygenase pathway), and epoxides (via the cytochrome P450 pathway). Binds to G-protein α-subunits in a covalent, posttranslational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Precursor for prostaglandins, prostacyclin, and thromboxane. Binds to G-protein α-subunits in a covalent, post-translational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Modulates nitric oxide production by prostaglandin synthesis via the cyclooxygenase pathway. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target Ras-GAP Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Harmful (C) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. |
| Other Notes【其他说明】 | Hallak, H., et al. 1994. J. Biol. Chem. 269, 4713. Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480. Han, J.-W., et al. 1991. Science252, 576. Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325. Neddleman P., et al. 1986. Annu. Rev. Biochem.55, 69. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥99% (TLC and GC) |
| form【形式】 | oil |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | colorless |
| solubility【溶解性】 | ethanol: 5 mg/mL |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| InChI | 1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6+,10-9+,13-12+,16-15+ |
| InChI key | YZXBAPSDXZZRGB-CGRWFSSPSA-N |
| packaging【包装】 | 100 mg in Glass bottle 1 g in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
| Flash Point(F)【闪点(F)】 | 235.4 °F - closed cup |
| Flash Point(C)【闪点(C)】 | 113 ℃ - closed cup |
